Pain affects more people than diabetes, heart disease, and cancer combined, and is the most common reason people seek medical attention

• Chronic pain and PTSD coexist

• Pain is a feeling of an unpleasant reality and PTSD involves reliving of painful events

• Both conditions entail the rewiring of neural circuits, resulting in maladaptive plasticity

• NMDA subtype of glutamate receptors play a vital role in the remodeling of these circuits

• Thus NMDA receptor modulators can bridge the gap between NSAIDs and opioids

• We are committed to building this bridge